Disease burden of recurrent cystitis infections on YOU and the healthcare systems

Burden on YOU

1 in 2 women icon

1 in 2 women of all ages will experience at least one episode of cystitis during their lifetime

1 in 3 will suffer from at least one recurrent cystitis icon

Of these women, almost 1 in 3 will suffer from at least one recurrent cystitis

DB Grafik

In a patient web-based study (GESPRIT) performed in 5 countries by woman like YOU affected by recurrent cystitis:

  • Anonymous, self-administered web-based survey
  • Aim: to evaluate the social & economic burden of recurrent cystitis as well as impact on quality of life
  • 5 countries involved (Germany, Switzerland, Poland, Russia, Italy)
  • 1,941 adult women who had experienced recurrent cystitis and were currently affected by acute cystitis (1,275) or within 4 weeks of study entry (666)


The following topics were covered in the GESPRIT questionnaire:

  • Demographics

  • Disease and disease burden (self-reported disease history)

  • Knowledge – Use Willingness (antibiotic use and prevention)

  • Socio-economic aspects

  • Quality of Life Burden of illness

  • Other personal information (marital status, employment, income)

Impact on daily activities

Women…

impact urinary infections intimate relations

…stated their intimate relations were negatively influenced by the disease

Women…

impact urinary infections sexual intercourse

…suffered cystitis very often or often after sexual intercourse

Premenopausal women…

impact urinary infections social handicap

…reported being socially handicapped

Burden on healthcare and society

Impact on mental well-being

impact urinary infections mental well being

The sudden, unforeseeable, and distressing nature of painful cystitis episodes often causes patients anxiety.


  • The resulting social handicap is known to induce feelings of self-devaluation or culpability, which can lead to clinical symptoms of depression
  • Mental health scores are below average in up to 81% of women, regardless of the presence of an acute infection or not
  • Up to 71% of women suffering from rUTIs exhibited some degree of depression at baseline


Main symptoms reported by women are:

Main Sympthoms

Performed in 5 countries by individuals:

  • 93.7% Pain and/or burning sensation when passing urine or at urinating
  • 82.4% Pollakiuria
  • 80.1% Dysuria
  • 29.8% Asthenia

Women with UTIs were willing to try any sort of prophylactic measure to limit antibiotic consumption.

Find out more about the burden of recurrent cystitis.

Burden of UTIs

Burder urinary tract infections logo
  • In the US, cystitis are responsible for 7 million medical visits a year, including 2 million for cystitis alone, with a total estimated cost of $3.5 billion.
  • In Europe, patients visit the doctors 3 times / year, costing an estimated €1.5 billion.
  • A mean of 3 days per year of sick leave are due to cystitis in Europe.

Burden of antibiotics

Burden of antimicrobials logo
  • 80.3% of patients suffering from cystitis had been treated at least once with antibiotics for UTIs.
  • In the US, 3 million patients suffering from cystitis are treated with antibiotics.
  • Individuals who had to change antibiotic treatment due to lack of efficacy was high (up to 53.2%).

And what about recurrences?

Doctors tend to see cases of cystitis in isolation and don’t see the recurrences, however, for patients even one recurrence is too much. RECAP

Patient's perspective

Patients perspective icon
  • 100% of women surveyed were willing to try any sort of prophylactic measure in place of antibiotics
  • For example, 52% were willing to try immunostimulants
  • At time of consultation, 74% of women had even already undertaken some kind of preventative measure

Doctors’ perspective

Doctors perspective cystitis picto
  • Every episode is seen as an acute one without treating recurrence. RECAP
  • Cystitis may not be a priority for all doctors. RECAP
  • Doctors do not advise starting prophylaxis until patients have experienced a mean 4-5 infections and discuss with him your
    need to reduce your burden. RECAP

Consult your doctor to know more about prevention of recurrent cystitis

A call for action

  • Recurrent cystitis have a significant impact on health related quality of life

  • They comprise a wide health and economic burden, this is why it is important not to underestimate the broad impact of recurrent cystitis
  • Effective approaches to manage recurrent uncomplicated cystitis do exist. Effective management is shown to be associated with an improved quality of life. Therefore, ask your doctor for help.

References

RECAP = Where a claim is followed by the RECAP, this means that this claim is endorsed by the RECAP board of experts.

OM Pharma Logo

The RECAP board is a panel of international experts in urological infections. The opinions presented within this educational material are those of the RECAP board and not those of OM Pharma. Members of the RECAP board include: Jose Tiran Saucedo (Mexico), Yvette León (Mexico), Gernot Bonkat (Switzerland), Kurt G. Naber (Germany), Florian ME. Wagenlehner (Germany), J C. Nickel (Canada), Flavia Rossi (Brazil), Enrique Ubertazzi (Argentina), Agnaldo L. da Silva Filho (Brazil), Tamara S. Perepanova (Russia), Bela Köves (Hungary) & Tommaso Cai (Italy).

Patient version : MED-HQ-UV-2100071 / HCP version : MED-HQ-UV-2100070
Date of preparation: December 2021